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Oscillatory Ca signal and histamine release in rat basophilic leukemia (RBL-2H3) cells

โœ Scribed by K. Maeyama; S. Yagi; M. Sasaki; E. Sakurai; T. Watanabe


Book ID
115884340
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
107 KB
Volume
183
Category
Article
ISSN
0014-2999

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โœ Kazutaka Maeyama; Masayuki Sasaki; Takehiko Watanabe ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 874 KB

In rat basophilic leukemia cells (RBL-2H3), a tumor analogue of mast cells, the aggregation of IgE receptors initiates increase in the intracellular concentration of calcium ([Ca2+]i), monitored with the fluorescent Ca probe fura-2, and finally results in histamine secretion. In cell suspensions, ho