Ortho-selectivity in SNAr substitutions
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Michael D. Wendt; Aaron R. Kunzer
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Article
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2010
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Elsevier Science
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French
โ 431 KB
The nucleophilic addition of organic anions to aromatic compounds with halogens positioned both ortho and para to activating groups was studied in a variety of solvents. Substrates showed strong preferences for ortho substitution in most cases. Evidence is presented for activating group-dependent co