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Orphan Peak Analysis: A Novel Method for Detection of Point Mutations Using an Automated Fluorescence DNA Sequencer

✍ Scribed by Masahira Hattori; Asami Shibata; Katsuji Yoshioka; Yoshiyuki Sakaki


Book ID
115611451
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
235 KB
Volume
15
Category
Article
ISSN
0888-7543

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Several approaches are now available for screening populations for known mutations in a given gene. However, for detection of multiple mutations in a population that has not been characterized or for detection of new mutations, the value and efficiency of these screening procedures decreases. Althou