High-resolution 1H NMR and magic angle s
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S. Garrod; E. Humpher; S.C. Connor; J.C. Connelly; M. Spraul; J.K. Nicholson; E.
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Article
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2001
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John Wiley and Sons
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English
⚖ 281 KB
## Abstract The metabolic consequences of xenobiotic‐induced toxicity were investigated using high‐resolution magic angle spinning (MAS) NMR spectroscopy of intact tissue. Renal papillary necrosis (RPN) was induced in Sprague‐Dawley rats (n = 12) via a single i.p. dose of 250 mg/kg 2‐bromoethanamin