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A study of metabolic compartmentation in the rat heart and cardiac mitochondria using high-resolution magic angle spinning 1H NMR spectroscopy

✍ Scribed by M.E Bollard; A.J Murray; K Clarke; J.K Nicholson; J.L Griffin


Book ID
117105783
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
479 KB
Volume
553
Category
Article
ISSN
0014-5793

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## Abstract It is shown that high‐resolution ^1^H NMR spectra of intact excised tissues and organs can be obtained by rotating the sample slowly about an axis at the magic angle of 54Β°44β€² with the external magnetic field. In this way tissue and cellular damage invoked by standard magic angle spinni

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It is demonstrated that a high-resolution (1)H NMR spectrum of excised rat liver can be obtained using the technique of magic angle turning (MAT) at a sample spinning rate of 1 Hz. A variant of the phase-corrected MAT (PHORMAT) pulse sequence that includes a water suppression segment was developed f