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Origin of Delayed Development of Drug Metabolism in the Newborn Rat

✍ Scribed by FEUER, G.; LISCIO, A.


Book ID
109667830
Publisher
Nature Publishing Group
Year
1969
Tongue
English
Weight
318 KB
Volume
223
Category
Article
ISSN
0028-0836

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## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t