Organoselenium chemistry. Dealkylation of amines with benzeneselenol
โ Scribed by Reich, Hans J.; Cohen, Martin L.
- Book ID
- 120257977
- Publisher
- American Chemical Society
- Year
- 1979
- Tongue
- English
- Weight
- 553 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A mild, facile cleavage of appropriately substituted tertiary, benzylic amines with acid chlorides is desodbed for both solution and solid phase.
Phenyl chlorothionoformate reacts rapidly with aliphatic amines at 20ยฐC to give a thiourethane and an alkyl chloride. The urethanes are readily converted to the secondary amine salt by reaction with dimethyl sulfate, followed by hydrolysis with water. Rates of reaction, and alkyl group cleavage sele
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