✦ LIBER ✦

Organopalladium approaches to prostaglandins. 4. Synthesis of the first interphenylene PGH2 analogs via benzylpalladation

✍ Scribed by Richard C. Larock; Srinivasan Babu

Publisher: Elsevier Science
Year: 1985
Tongue: French
Weight: 145 KB
Volume: 26
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)94905-0

No coin nor oath required. For personal study only.

✦ Synopsis

The reaction of norbornene, norbornadiene and 7-oxanorbornene with methyl 3-(chloromet y phenoxyacetate, (S)-l-octyn-3-01 and 8% Pd(PPh3)4 affords in one step satisfactory yields of the corresponding, first interphenylene PGH2 analogs.

📜 SIMILAR VOLUMES

Organopalladium approaches to prostaglan

Organopalladium approaches to prostaglandins. 2. Synthesis of prostaglandin endoperoxide analogs via π-allylpalladium additions to bicyclic olefins

✍ R.C. Larock; J.P. Burkhart; K. Oertle 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 265 KB

Organopalladium approaches to prostaglan

Organopalladium approaches to prostaglandins. 1. Synthesis of thiophene-containing prostaglandin endoperoxide analogs via thienylpalladation of bicycle olefins

✍ R.C. Larock; D.R. Leach; S.M. Bjorge 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 216 KB

Thlophene-contalnlng prostaglandln endoperoxlde analogs are readily avallable by addltlon of thlenylpalladlum species to blcycllc oleflns and subsequent treatment with alkenyl or alkynyl organometalllcs. Hydrogenation affords blcycllc and trlcycllc prostanolc acid analogs.