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Organoiridium catalysed hydrogen isotope exchange of benzamide derivatives

✍ Scribed by Jacob S. Valsborg; Lone Sørensen; Christian Foged

Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
959 KB
Volume
44
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Hydrogen‐tritium exchange in a series of benzamide derivatives and acetanilide has been investigated using [Ir(cod)(Cy~3~P)(Py)]PF~6~ as catalyst. Specific activities of 6–43 Ci/mmol were obtained. Tritium NMR spectroscopy showed that exchange occurred ortho to the amide group. Copyright © 2001 John Wiley & Sons, Ltd.

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