Organocatalytic conversion of arylglyoxa
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Ellen Schmitt; Ingo Schiffers; Carsten Bolm
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Article
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2009
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Elsevier Science
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French
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A novel protocol for the organocatalytic conversion of arylglyoxals into the corresponding a-hydroxy arylacetic acid methyl esters has been developed. The catalyst consists of a combination of a commercially available cinchona alkaloid derivative and an achiral thiol and leads to enantiomerically en