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Organocatalytic Enantioselective Friedel−Crafts Reactions of 1-Naphthols with Aldimines

✍ Scribed by Liu, Guixia; Zhang, Shilei; Li, Hao; Zhang, Tangzhi; Wang, Wei

Book ID
120291512
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
754 KB
Volume
13
Category
Article
ISSN
1523-7060

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✍ Pankaj Chauhan; Swapandeep Singh Chimni 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 1 views

## Abstract The first organocatalytic asymmetric aza‐Friedel–Crafts reaction of naphthols with __N__‐sulfonyl imines has been developed. The cupreine‐derived bifunctional organocatalyst BzCPN efficiently catalyzes the formation of aza‐Friedel–Crafts products in good to excellent yields (up to 99 %)