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Organocatalytic Asymmetric α-Aminoxylation/Aza-Michael Reactions for the Synthesis of Functionalized Tetrahydro-1,2-oxazines

✍ Scribed by Min Lu; Di Zhu; Yunpeng Lu; Yuxuan Hou; Bin Tan; Guofu Zhong


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
192 KB
Volume
120
Category
Article
ISSN
0044-8249

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## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c