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Organization, Sequence and Expression of the HLA-B27 Gene: A Molecular Approach to Analyze HLA and Disease Associations

✍ Scribed by Weiss, Elisabeth H.; Kuon, W.; Dörner, C.; Lang, M.; Riethmüller, G.


Book ID
121263658
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
781 KB
Volume
170
Category
Article
ISSN
0171-2985

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Insight into the mechanism of involvement of HLA-B27 in ankylosing spondylitis (AS) (Brewerton et al. 1973, Schlosstein et al. 1973) has previously been hampered by the inability to directly examine the HLA-B27 gene and/or contiguous genetic sequences. Accordingly, we investigated the HLA-B27 gene b