𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Organization and expression of H1 histone and H1 replacement histone genes

✍ Scribed by D. Doenecke; W. Albig; H. Bouterfa; B. Drabent

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
951 KB
Volume
54
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The H1 family is the most divergent subgroup of the highly conserved class of histone proteins [Cole: Int J Pept Protein Res 30:433–449, 1987]. In several vertebrate species, the H1 complement comprises five or more subtypes, and tissue specific patterns of H1 histones have been described. The diversity of the H1 histone family raises questions about the functions of different H1 subtypes and about the differential control of expression of their genes. The expression of main type H1 genes is coordinated with DNA replication, whereas the regulation of synthesis of replacement H1 subtypes, such as H1Β° and H5, and the testis specific H1t appears to be more complex. The differential control of H1 gene expression is reflected in the chromosomal organization of the genes and in different promoter structures. This review concentrates on a comparison of the chromosomal organization of main type and replacement H1 histone genes and on the differential regulation of their expression. General structural and functional data, which apply to both H1 and core histone genes and which are covered by recent reviews, will not be discussed in detail.

πŸ“œ SIMILAR VOLUMES

Histone genes in higher plants: Organiza
Histone genes in higher plants: Organization and expression
✍ Chaubet, Nicole ;Chaboute, Marie-Edith ;Philipps, Gabriel ;Gigot, Claude πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 850 KB

The general structure of the plant histone genes has been deduced from the comparison of the nucleotide sequences of ten H3 and H4 genes of maize (3 H3 and 3 H4) and Arubidopsis rhaliuna (2 H3 and 2 H4). The five H3 and five H4 genes encode the same proteins, respectively. The 5'-flanking regions co

Nucleotide sequences of two corn histone
Nucleotide sequences of two corn histone H3 genes. Genomic organization of the corn histone H3 and H4 genes
✍ Nicole Chaubet; Gabriel Philipps; Marie-Edith Chaboute; Martine Ehling; Claude G πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 851 KB

Two histone H3 genes have been cloned from a XgtWESX.B corn genomic library. The nucleotide sequences show 96Β°7o homology and both encode the same protein, which differs from its counterpart in wheat and pea by one amino acid substitution. The 5'-flanking regions of the two corn H3 genes contain the

Association of a human H1 histone gene w
Association of a human H1 histone gene with an H2A pseudogene and genes encoding H2B.1 and H3.1 histones
✍ Efterpi Kardalinou; Stefan Eick; Werner Albig; Detlef Doenecke πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 730 KB

## Abstract A cluster of human histone genes was found on three overlapping clones isolated from cosmid and bacteriophage libraries. These three overlapping segments of the human genome comprise genes coding for H3.1, an H2A pseudogene, and an H2B.1 gene downstream of the previously characterized H

Histone H1Β° Ribosomal RNA Synthesis and
Histone H1Β° Ribosomal RNA Synthesis and Cell Differentiation
✍ R.A. Flickinger πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 107 KB

It is proposed that histone H1Β°prevents binding of the rRNA transcription factor UBF to regulatory sequences of the rRNA gene. This has a role in reducing rRNA synthesis and inhibiting cell proliferation. This affords the opportunity for other mechanisms to promote cell differentiation.