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Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice

✍ Scribed by Roni Haklai; Galit Elad-Sfadia; Yaakov Egozi; Yoel Kloog


Book ID
105992608
Publisher
Springer
Year
2007
Tongue
English
Weight
416 KB
Volume
61
Category
Article
ISSN
0344-5704

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The effects of a new metalloproteinase inhibitor, BE 16627B [L-N-(N-hydroxy-2-isobutylsuccinynamoyl)-se~l-L-valine, M W 375.21 isolated from microbial cultures, on human tumor cell growth in nude mice were investigated. BEl6627B inhibited metalloproteinases in enzyme assays, as well as gelatinolysis