𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Orally active .beta.-lactam inhibitors of human leukocyte elastase. 2. Effect of C-4 substitution

✍ Scribed by Hagmann, William K.; Kissinger, Amy L.; Shah, Shrenik K.; Finke, Paul E.; Dorn, Conrad P.; Brause, Karen A.; Ashe, Bonnie M.; Weston, Hazel; Maycock, Alan L.


Book ID
125975597
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
954 KB
Volume
36
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Inhibition of human leukocyte elastase b
✍ Caroline Doucet; Isabelle Vergely; MichΓ¨le Reboud-Ravaux; Jean Guilhem; Randa Ko πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 840 KB

3R)-and (3S)-N-(2-chloromethylphenyl)-3-bromo-3-fluoroazetidin-2-ones 2 were synthesized via the separation of diastereoisomeric phenylglycinol derivatives of the starting 2,3-dibromo-2-fluoropropanoic acid. Acidic hydrolysis of the hydroxyamides led to the chiral trihalogenopropanoic acids. Then, a