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Oral pemphigus vulgaris associated with HIV infection

✍ Scribed by Tim A Hodgson; Sarah J Fidler; Paul M Speight; Jonathan N Weber; Stephen R Porter


Book ID
117850116
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
171 KB
Volume
49
Category
Article
ISSN
1097-6787

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Neonatal pemphigus vulgaris associated w
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We report a neonate with immunofluorescence-proven pemphigus vulgaris. The condition presented at birth with widespread skin erosions and ulceration of the oral mucosa. Histopathological and immunofluorescence studies confirmed pemphigus vulgaris. The mother had mild oral pemphigus vulgaris treated

Neonatal pemphigus vulgaris with extensi
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The clinical phenotype of pemphigus is well explained by the combination of desmoglein (Dsg) 1 and Dsg3 distribution pattern and antiDsg autoantibody profile (Dsg compensation theory). It has been reported that neonatal skin has a similar Dsg distribution pattern to adult mucosal epithelia. We descr