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Neonatal pemphigus vulgaris associated with mild oral pemphigus vulgaris in the mother during pregnancy

✍ Scribed by Chowdhury; Natarajan

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
325 KB
Volume
139
Category
Article
ISSN
0007-0963

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✦ Synopsis

We report a neonate with immunofluorescence-proven pemphigus vulgaris. The condition presented at birth with widespread skin erosions and ulceration of the oral mucosa. Histopathological and immunofluorescence studies confirmed pemphigus vulgaris. The mother had mild oral pemphigus vulgaris treated during pregnancy with topical corticosteroids. All the neonate's skin erosions had crust formation at day 2 but healed completely within 2 weeks.

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Neonatal pemphigus vulgaris with extensi
Neonatal pemphigus vulgaris with extensive mucocutaneous lesions from a mother with oral pemphigus vulgaris
✍ A. Campo-Voegeli; F. Muñiz; J.M. Mascaró Jr; M. Casals; F. García; J.L. Arimany; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB

The clinical phenotype of pemphigus is well explained by the combination of desmoglein (Dsg) 1 and Dsg3 distribution pattern and antiDsg autoantibody profile (Dsg compensation theory). It has been reported that neonatal skin has a similar Dsg distribution pattern to adult mucosal epithelia. We descr

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A study of desmoglein 1 autoantibodies in pemphigus vulgaris: racial differences in frequency and the association with a more severe phenotype
✍ K.E. Harman; M.J. Gratian; B.S. Bhogal; S.J. Challacombe; M.M. Black 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 308 KB

## Background: Pemphigus vulgaris (pv) is characterized by pathogenic autoantibodies to desmoglein (dsg) 3, but additional antibodies to dsg1, the pemphigus foliaceus antigen, are detectable in some cases. ## Objectives: To investigate the clinical significance of the presence of both dsg 1 and 3