Oral cancer in 57,518 industrial workers of Gujarat, India. A prevalence and followup study

✍ Scribed by A. M. Malaowalla; Sol Silverman Jr.; N. J. Mani; K. F. Bilimoria; Lowell W. Smith

• Publisher: John Wiley and Sons
• Year: 1976
• Tongue: English
• Weight: 368 KB
• Volume: 37
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197604)37:4<1882::aid-cncr2820370437>3.0.co;2-2

✦ Synopsis

I n Gujarat, India, 57,518 industrial workers over 35 years old were examined for oral lesions. At a two-year interval, 43,654 workers were re-examined. Biopsies were taken from 13,223 lesions. I n the initial examination, 29 oral cancers were diagnosed, representing a prevalence rate of 50/100,000. After two years, 22 new oral cancers were diagnosed, representing a n incidence rate of 25/100,000 per year. Over 90% were squamous carcinomas, with the majority of lesions occurring i n the oropharynx a n d tongue. All patients who developed squamous carcinomas had tobacco habits, while 85% of the entire study population h a d oral habits in some form. Their most common habits were smoking tobacco alone or in combination with chewing "pan"/"supari." Of the carcinomas that developed during a two-year interval, 62% appeared i n previously normal appearing mucosa. Leukoplakia was the only oral lesion that proved t o be precancerous, with a transformation rate of 0.13% in a two-year interval.