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OR.45. Induction of Autoantigen-Specific Cd4+Cd25+ Regulatory T‐Cells In Vitro

✍ Scribed by Mindi Walker; Bryan Carson; Steven Ziegler; Gerald Nepom; Jane Buckner

Book ID: 113539166
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 48 KB
Volume: 119
Category: Article
ISSN: 1090-2341
DOI: 10.1016/j.clim.2006.04.201

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## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR