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OR.31. Human TIM-3 Regulates Th1 and Th17 Cytokines

✍ Scribed by William Hastings; David Anderson; Vijay Kuchroo; David Hafler

Book ID
113540799
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
38 KB
Volume
131
Category
Article
ISSN
1090-2341

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TIM-3 is expressed on activated human CD
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✍ William D. Hastings; David E. Anderson; Nasim Kassam; Ken Koguchi; Edward A. Gre πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 545 KB

## Abstract TIM‐3 is a molecule selectively expressed on a subset of murine IFN‐γ‐secreting T helper 1 (Th1) cells but not Th2 cells, and regulates Th1 immunity and tolerance __in vivo__. At this time little is known about the role of TIM‐3 on human T cells. To determine if TIM‐3 similarly identifi