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OR.25. Promotion of Proinflammatory Th1 and Th17 Responses by Tim-1 Expressed on Dendritic Cells

✍ Scribed by Sheng Xiao; Vijay Kuchroo

Book ID
113540176
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
38 KB
Volume
127
Category
Article
ISSN
1090-2341

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## Abstract TIM‐3 is a molecule selectively expressed on a subset of murine IFN‐γ‐secreting T helper 1 (Th1) cells but not Th2 cells, and regulates Th1 immunity and tolerance __in vivo__. At this time little is known about the role of TIM‐3 on human T cells. To determine if TIM‐3 similarly identifi