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Notch-ligand expression by NALT dendritic cells regulates mucosal Th1- and Th2-type responses

✍ Scribed by Yoshiko Fukuyama; Daisuke Tokuhara; Shinichi Sekine; Kosuke Kataoka; Jonathan D. Markham; Allyson R. Irwin; Grace H. Moon; Yuka Tokuhara; Keiko Fujihashi; Julia Davydova; Masato Yamamoto; Rebekah S. Gilbert; Kohtaro Fujihashi


Book ID
116302775
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
481 KB
Volume
418
Category
Article
ISSN
0006-291X

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## Abstract We have addressed the hypothesis that Notch ligands play a decisive role in determining the ability of antigen‐presenting cells to influence T cell polarization. Dendritic cells displayed distinct expression profiles of Delta and Jagged ligands for Notch when exposed to biologically rel