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Optimizing vaccine-induced CD8+ T-cell immunity: focus on recombinant adenovirus vectors

✍ Scribed by Bassett, Jennifer D; Swift, Stephanie L; Bramson, Jonathan L

Book ID
111643852
Publisher
Expert Reviews
Year
2011
Tongue
English
Weight
491 KB
Volume
10
Category
Article
ISSN
1476-0584

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## Abstract ## Background Virus‐vectored vaccine is a powerful activator of CD8 T cell‐mediated immunity and is especially amenable to respiratory mucosal immunization, offering hopes for use in humans with diminished helper CD4 T cell function. However, whether virus‐mediated mucosal immunization