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Skin-Derived Dendritic Cells Induce Potent CD8+ T Cell Immunity in Recombinant Lentivector-Mediated Genetic Immunization

โœ Scribed by Yukai He; Jiying Zhang; Cara Donahue; Louis D. Falo Jr.


Book ID
116570583
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
799 KB
Volume
24
Category
Article
ISSN
1074-7613

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Murine epidermis contains 2 distinct cell populations which contribute to the skin immune system, Langerhans cells (LC), and dendritic epidermal T cells (DETC). LCs are important in the induction of immunity against a wide range of antigens; however, the function of DETC is unclear. To investigate t