Optimizing the liquid chromatographic separation of major carboxylic acids in wine by a modelling surface response method

✍ Scribed by R.M. Marcé; M. Calull; J.C. Olucha; F. Borrull; F.X. Rius; J. Zupan

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 449 KB
• Volume: 259
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(92)85373-e

✦ Synopsis

The separation and deterrmnatlon of the major carboxyhc acids m wme by hqmd chromatography were optlmlzed by usmg the modelhng surface response method The chromatographlc response functton was used as a crttenon to obtam an optimum peak separation with the munmum analysis time accepted The startmg mobde phase composltron (% methanol) and the change m the solvent strength of the mobile phase during the analysis time were consldered as experunental parameters Mahc, tartanc, acetic, lactic, snccm~c and cltnc acid were determmed by hnear gradlent elutlon of then phenacyl bromide dertvatlves The optmuzed method was apphed to a red wme sample