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Optimizing Surgical and Imatinib Therapy for the Treatment of Gastrointestinal Stromal Tumors

✍ Scribed by Sicklick, Jason K.; Lopez, Nicole E.


Book ID
120682314
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
571 KB
Volume
17
Category
Article
ISSN
1091-255X

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πŸ“œ SIMILAR VOLUMES


Systemic therapy for advanced gastrointe
✍ Edward J. Kim; Mark M. Zalupski πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 88 KB

## Abstract Progression on first‐line therapy with imatinib in gastrointestinal stromal tumors (GIST) is caused by either initial resistance or more often a secondary mutation in tyrosine kinases KIT or PDGFR. Therapies in development for imatinib‐resistant GIST include agents that target KIT/PDGFR