𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Surgical interventions for focal progression of advanced gastrointestinal stromal tumors during imatinib therapy

✍ Scribed by Junichi Hasegawa; Tatsuo Kanda; Seiichi Hirota; Masafumi Fukuda; Akiko Nishitani; Tsuyoshi Takahashi; Isao Kurosaki; Shusaku Tsutsui; Katsuyoshi Hatakeyama; Toshirou Nishida


Publisher
Springer
Year
2007
Tongue
English
Weight
224 KB
Volume
12
Category
Article
ISSN
1341-9625

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Systemic therapy for advanced gastrointe
✍ Edward J. Kim; Mark M. Zalupski πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 88 KB

## Abstract Progression on first‐line therapy with imatinib in gastrointestinal stromal tumors (GIST) is caused by either initial resistance or more often a secondary mutation in tyrosine kinases KIT or PDGFR. Therapies in development for imatinib‐resistant GIST include agents that target KIT/PDGFR