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Optimizing chemotherapy for transitional cell carcinoma by application of bcl-2 and bcl-xL antisense oligodeoxynucleotides

✍ Scribed by Christian Bolenz; Andreas Becker; Lutz Trojan; Axel Schaaf; Yanwei Cao; Christel Weiss; Peter Alken; Maurice Stephan Michel


Book ID
116956079
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
475 KB
Volume
25
Category
Article
ISSN
1078-1439

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## Abstract Our study was designed to investigate the role of the anti‐apoptotic proteins Bcl‐2 and Bcl‐xL in the chemoresistance of cells derived from malignant pleural mesothelioma. First, we determined the basal expression levels of Bcl‐2 and Bcl‐xL in mesothelioma cells and examined the effect