Optimized spiral imaging for measurement of myocardial T2 relaxation

✍ Scribed by Warren D. Foltz; Osama Al-Kwifi; Marshall S. Sussman; Jeff A. Stainsby; Graham A. Wright

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 606 KB
• Volume: 49
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.10467

✦ Synopsis

Abstract

Microcirculation oxygen levels and blood volumes should be reflected in measurements of myocardial T~2~ relaxation. This work describes the optimization of a spiral imaging strategy for robust myocardial T~2~ measurement to minimize the standard deviation of T~2~ measurement (σ__T__~2~). Theoretical and experimental studies of blurring at muscle/blood interfaces enabled the derivation of parameter sets which reduce σ T~2~ to the level of 5%. T~2~ relaxation mapping within healthy volunteers provided estimation of residual σ__T__~2~ within the optimized technique. The standard deviation in T~2~ measurement across regions of interest (ROIs) in different locations is about 9%. The standard deviation in T~2~ measurement in an ROI across different time points is about 5%. Magn Reson Med 49:1089–1097, 2003. © 2003 Wiley‐Liss, Inc.