✦ LIBER ✦

On the measurement of multi-component T2 relaxation in cartilage by MR spectroscopy and imaging

✍ Scribed by ShaoKuan Zheng; Yang Xia

Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 653 KB
Volume: 28
Category: Article
ISSN: 0730-725X
DOI: 10.1016/j.mri.2009.12.006

No coin nor oath required. For personal study only.

✦ Synopsis

The multicomponent T 2 relaxation in bovine nasal cartilage (BNC) was investigated by nuclear magnetic resonance spectroscopy using the Carr-Purcell-Meiboom-Gill (CPMG) sequence and microscopic magnetic resonance imaging (μMRI) method using a CPMG-SE imaging sequence. All experimental data were analyzed by the non-negative least square (NNLS) procedure. Only one T 2 component was found in BNC by both experimental methods (about 113 and 170 ms before and after being enzymatically digested by trypsin). Several experimental and specimen-related factors were investigated in this study, and it was found that some of them could produce artificial multi-component T 2 , including the use of the standard MSME imaging sequence at certain imaging gradients.

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