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Effects of the interaction between ferric iron and L-dopa melanin on T1 and T2 relaxation times determined by magnetic resonance imaging

✍ Scribed by Jeffrey M. Tosk; Barbara A. Holshouser; Roland C. Aloia; David B. Hinshaw Jr.; Anton N. Hasso; James P. Macmurray; A. Douglas Will; Louis P. Bozzetti


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
398 KB
Volume
26
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

T1 and T2 relaxation times of agar phantoms containing L‐dopa melanin and Fe^3+^ were measured under MRI conditions. Fe^3+^ shortened T1 and T2 relaxation times. Melanin influenced relaxation times only in the presence of Fe^3+^; thus, contrast in MR images of the basal ganglia may depend upon levels of both paramagnetic iron and neuromelanin.