Optimized Procedure for the Cross-Aldol Condensation of Reactive Aldehydes
β Scribed by Boris, ; Kohler, A. B.
- Book ID
- 121195038
- Publisher
- Taylor and Francis Group
- Year
- 1985
- Tongue
- English
- Weight
- 110 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0039-7911
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π SIMILAR VOLUMES
enolsilanes 1 does not govern the stereochemistry of aldol condensation products. We recently reported for the first time', acetals la6'8, that compounds 2, structural analogous of add to aldehydes and Schiff bases in a cross-aldol type condensation, to afford B-hydroxyacids and B-Lactams respective
In the presence of catalytic amount of chiral Ti(OiPr) 4 /BINOL (0.08 equiv.) the asymmetric aldol condensation of 6-methyl-4H-[1,3]-dioxin-4-one-derived silyloxydienes takes place in high yields and enantiomeric excesses with aromatic, heteroaromatic, unsaturated and aliphatic aldehydes. Notable am