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Optimization of the Relaxivity of MRI Contrast Agents: Effect of Poly(ethylene glycol) Chains on the Water-Exchange Rates of Gd III Complexes

✍ Scribed by Doble, Dan M. J.; Botta, Mauro; Wang, Jay; Aime, Silvio; Barge, Alessandro; Raymond, Kenneth N.


Book ID
120814108
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
39 KB
Volume
123
Category
Article
ISSN
0002-7863

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Effect of a mesitylene-based ligand cap
✍ Eric J. Werner; Mauro Botta; Silvio Aime; Kenneth N. Raymond πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 481 KB

## Abstract A series of new Gd(III) hydroxypyridonate complexes featuring a mesitylene (ME)‐derived ligand cap has been prepared. Relaxometric characterization reveals that the complexes tend to form large aggregates in solution with slow tumbling rates, as estimated from NMRD analysis, and unique