✦ LIBER ✦

Optimization of survey protocols for mri

✍ Scribed by Elliot R. Mcveigh; R. Mark Henkelman; Michael J. Bronskill

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 815 KB
Volume: 13
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910130202

No coin nor oath required. For personal study only.

✦ Synopsis

A method for evaluating the sensitivity of MRI protocols to changes in an arbitrary number of tissue parameters over a broad range of parameter values is presented. This analysis is useful for choosing an optimal basis set ofimages for either a "survey" protocol or tissue segmentation algorithms. A survey protocol is required when searching for a lesion of unknown type or location. Segmentation requires unique signal signatures for tissues that may cover a broad range of tissue parameter values. Data acquisition is modeled as a mapping of a domain of tissue parameter values into a signal manifold in a signal strength space defined by the MRI protocol. The efficacy of the protocol is evaluated by investigating the characteristics of the signal manifold. A figure of merit which maximizes the probability of discriminating each point in the domain of tissue parameters from all others is developed.

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