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Optimization of nucleophilic fluorination step in the synthesis of various compounds labelled with fluorine-18 for their use as pet radiotracers

✍ Scribed by N. A. Gomzina; V. V. Zaitsev; R. N. Krasikova

Book ID
112132772
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
174 KB
Volume
44
Category
Article
ISSN
0022-2135

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The development of rapid radiolabeling techniques under mild reaction conditions involving the shortlived positron emitter fluorine-18 remains a special challenge in organic PET chemistry. This work describes a novel and facile application of the traceless Staudinger ligation as a mild and versatile