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Optimization of fed-batch culture by dynamic programming and regression analysis

โœ Scribed by M. Kishimoto; T. Yoshida; H. Taguchi

Publisher
Springer Netherlands
Year
1980
Tongue
English
Weight
434 KB
Volume
2
Category
Article
ISSN
0141-5492

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โœฆ Synopsis

An algorithm

for the optimization of a fermentation process was studied using the combination of dynamic programming and linear predictive procedure by regression analysis.

It was applied to the fed-batch culture for glutamic acid production with ethanol feeding, the results of which proved that it was effective for the optimization problems.

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## a b s t r a c t In fed-batch culture of glycerol bio-dissimilation to 1, 3-propanediol (1, 3-PD), the aim of adding glycerol is to obtain as much 1, 3-PD as possible. So a proper feeding rate is required during the process. Taking the concentration of 1, 3-PD at the terminal time as the performa