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Optimization of DNA immobilization on gold electrodes for label-free detection by electrochemical impedance spectroscopy

✍ Scribed by Simon D. Keighley; Peng Li; Pedro Estrela; Piero Migliorato

Book ID: 108071911
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 335 KB
Volume: 23
Category: Article
ISSN: 0956-5663
DOI: 10.1016/j.bios.2007.11.012

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## Abstract The short sequence related to hepatitis C virus (HCV1) is detected by a label‐free DNA hybridization biosensor. The sensor relies on the immobilization of a 20‐mer oligonucleotide containing 2 guanine and 11 cytosine bases denoted PHCV1 as probe on the pencil graphite electrode (PGE). T