Optimization and Development of a Core-in-Cup Tablet for Modulated Release of Theophylline in Simulated Gastrointestinal Fluids
โ Scribed by Danckwerts, M. P.
- Book ID
- 120563349
- Publisher
- Informa plc
- Year
- 2000
- Tongue
- English
- Weight
- 123 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0363-9045
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A new core-in-cup tablet that is manufactured from a novel adjustable punch, has been formulated and evaluated for its ability to release with subsequent absorption of theophylline via a zero-order rate of absorption. The core-in-cup tablets were compared with core only tablets and immediate release
In vitro dissolution testing of solid pharmaceutical dosage forms has become a routine aspect of data collection for new product submissions and quality control purposes. With increasing frequency, dissolution testing is performed in buffered media, including low pH simulated gastric fluid and/or al