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Optimisation and sensitivity of single-stranded conformation polymorphism for the detection of hepatitis C virus quasi-species

โœ Scribed by Victoria M. McKechnie; Elizabeth A.B. McCruden


Book ID
114139605
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
373 KB
Volume
92
Category
Article
ISSN
0166-0934

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In patients infected with the hepatitis C virus (HCV), a heterogeneous population of viruses, so-called quasispecies exists in vivo. The hypervariable regions (HVR) within the second envelope gene (HCV-E2) show particularly highly intratypic variability and are considered to be the target of neutral