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Optimal design allocations for estimating area under curves for studies employing destructive sampling

โœ Scribed by Walter W. Piegorsch; A. John Bailer

Book ID
112473248
Publisher
Springer
Year
1989
Tongue
English
Weight
756 KB
Volume
17
Category
Article
ISSN
1573-8744

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Randomization Tests for Assessing the Equality of Area Under Curves for Studies Using Destructive Sampling
โœ A. John Bailer; Stephen J. Ruberg ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 407 KB ๐Ÿ‘ 2 views

Testing the equality of the area under a curve (AUC) for different dose groups is frequently done in pharmacokinetic research. Equality of AUCs is one indicator of bioequivalence. When the experimental unit must be sacrificed to obtain a response, AUC can be simply estimated using a linear combinati