A LIMITED SAMPLING METHOD FOR THE ESTIMA
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IFTEKHAR MAHMOOD; J. TODD SAHLROOT
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Article
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1997
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John Wiley and Sons
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English
⚖ 553 KB
A limited sampling model has been developed for ¯unarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f