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Estimation of the area under the concentration-time curve of racemic lansoprazole by using limited plasma concentration of lansoprazole enantiomers

✍ Scribed by Takenori Niioka; Masatomo Miura; Tsukasa Uno; Norio Yasui-Furukori; Makoto Hayakari; Tomonori Tateishi; Toshio Suzuki


Publisher
Springer
Year
2008
Tongue
English
Weight
164 KB
Volume
64
Category
Article
ISSN
0031-6970

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A limited sampling model has been developed for Β―unarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f