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Optimal controls for a model with pharmacokinetics maximizing bone marrow in cancer chemotherapy

✍ Scribed by Urszula Ledzewicz; Heinz Schättler

Book ID
116732718
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
359 KB
Volume
206
Category
Article
ISSN
0025-5564

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Since 1980, 75 patients with small-cell lung cancer (SCLC) have been entered into four consecutive studies of high-dose chemotherapy using autologous bone marrow transplantation (ABMT) to assist haematological recovery. In the first study, 25 patients were treated with cyclophosphamide (160-200 mg/k