✦ LIBER ✦

Optimal control strategy for the enhanced production of cellulase enzyme using the new mutant Trichoderma reesei E-12

✍ Scribed by S. K. Rakshit; V. Sahai

Book ID: 104743987
Publisher: Springer
Year: 1991
Tongue: English
Weight: 553 KB
Volume: 6
Category: Article
ISSN: 1615-7605
DOI: 10.1007/bf00369062

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✦ Synopsis

Cellulase enzyme production was enhanced using the mutant strain Trichoderma reesei, E-t2, which was shown to be partially resistant to catabolite repression. An optimal profile for pH, which was found to be the critical environmental parameter, was determined using a rigorous mathematical optimization procedure. Semi-empirical models were used to minimize complications in the computation. A 30% increase in enzyme activity and productivity was obtained using the optimal pH strategy as compared to the pH cycling strategy.

List of symbols

al,aa, a 3 d 1, d-e,d-3 a4,as,a 6

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