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Optimal Control of the Secondary Drying Stage of Freeze Drying of Solutions in Vials Using Variational Calculus

✍ Scribed by Sadikoglu, Hasan


Book ID
118032531
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
343 KB
Volume
23
Category
Article
ISSN
0737-3937

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A rigorous unsteady state and spatially multidimensional model is presented and solved to describe the dynamic behavior of the primary and secondary drying stages of the lyophilization of a pharmaceutical product in vials for different operational policies. The results in this work strongly motivate