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Optimal Control Applied to Cell-Cycle-Specific Cancer Chemotherapy

✍ Scribed by Panetta, John Carl; Fister, K. Renee

Book ID
118192756
Publisher
Society for Industrial and Applied Mathematics
Year
2000
Tongue
English
Weight
163 KB
Volume
60
Category
Article
ISSN
0036-1399

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πŸ“œ SIMILAR VOLUMES

State-constrained optimal control applie
State-constrained optimal control applied to cell-cycle-specific cancer chemotherapy
✍ M. Alamir; S. Chareyron πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 675 KB

## Abstract In this paper, the optimal drug injection problem arising in cancer treatment by cell‐cycle‐specific chemotherapy is investigated. The optimal control problem is state constrained in which the stage cost reflects the concern of maximal drug injection, while the state constraint imposes

Application of optimal control theory to
Application of optimal control theory to analysis of cancer chemotherapy regimens
✍ Alexey S. Matveev; Andrey V. Savkin πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 145 KB

Cancer chemotherapy with application of one drug is studied. The negative and inhibiting e ect of the tumor on normal cells is taken into account. Under certain assumptions, we determine the optimal regimen that minimizes the tumor burden at the end of a ΓΏxed period of therapy while maintaining the

Genetic variants in cell cycle control p
Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer
✍ Yuanqing Ye; Hushan Yang; H. Barton Grossman; Colin Dinney; Xifeng Wu; Jian Gu πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 155 KB

## Abstract ## BACKGROUND Cell cycle checkpoint regulation is crucial for the prevention of carcinogenesis in mammalian cells. ## METHODS To test the hypothesis that common sequence variants in the cell cycle control pathway may affect bladder cancer susceptibility, the effects of a panel of 10