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Optimal conditions for induction of certain mutation types inBrevibacterium flavumby N-Methyl-N’-nitro-N-nitrosoguanidine

✍ Scribed by J. Koníček; M. Koníčková-Radochová; M. Strnadová; J. Chaloupka; A. Wolf; V. Rytíř; J. Hubáček

Book ID
112939535
Publisher
Springer Netherlands
Year
1988
Tongue
English
Weight
466 KB
Volume
33
Category
Article
ISSN
0015-5632

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Simultaneous induction of multiple mutat
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✍ Isabel L. Calderón; Enrique Cerdá-Olmedo 📂 Article 📅 1982 🏛 Springer-Verlag 🌐 English ⚖ 668 KB

Contrary to what happens in bacteria, mutations induced by nitrosoguanidine in yeast are not accompanied by an excess of mutations in nearby genes. We have investigated nitrosoguanidine mutagenesis in three regions of the yeast genome: the contiguous DNA segments HIS4A, HIS4B and HIS4C, located on c