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Induction of the Petite Mutation in Saccharomyces cerevisiae by N-Methyl-N'-Nitro-N-Nitrosoguanidine

✍ Scribed by NORDSTROM, K.

Book ID
117998704
Publisher
Microbiology Society
Year
1967
Tongue
English
Weight
553 KB
Volume
48
Category
Article
ISSN
0022-1287

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✍ Isabel L. Calderón; Enrique Cerdá-Olmedo 📂 Article 📅 1982 🏛 Springer-Verlag 🌐 English ⚖ 668 KB

Contrary to what happens in bacteria, mutations induced by nitrosoguanidine in yeast are not accompanied by an excess of mutations in nearby genes. We have investigated nitrosoguanidine mutagenesis in three regions of the yeast genome: the contiguous DNA segments HIS4A, HIS4B and HIS4C, located on c