𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Optically active diethyl ester of α-aminobenzylphosphonic acid

✍ Scribed by S. V. Rogozhin; V. A. Davankov; Yu. P. Belov


Book ID
112423308
Publisher
Springer
Year
1973
Tongue
English
Weight
149 KB
Volume
22
Category
Article
ISSN
1573-9171

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Reverse chemoselective borane reduction
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Reduction of the 2-methyl-2-p-tolylmalonic monoester (+)-2 with the borane-dimethylsulfide complex took place unexpectedly on the ester function,providing the 8-hydroxy-acid (-)-3. This chemoselective reaction proceeded likely through formation of a six-membered ring monoacyloxyborane intermediate 6